The Uplay-r1-loader64.dll missing error can be frustrating, but it's not impossible to fix. By following the steps outlined in this article, you should be able to resolve the issue and enjoy Far Cry 4 without any problems. If none of the methods work, you may want to consider reaching out to Ubisoft support for further assistance. Remember to always keep your Uplay and game versions up to date to avoid any compatibility issues.
This is the most common cause.