– D-galactose is the sugar responsible for B specificity, whereas N-acetylgalactosamine confers A specificity.
Which class of immunoglobulin is primarily responsible for "naturally occurring" ABO antibodies?A) IgGB) IgAC) IgMD) IgE Multiple Choice Questions And Answers In Immunohematology
– Most "naturally occurring" antibodies, such as Anti-A and Anti-B, are IgM and react optimally at room temperature. – D-galactose is the sugar responsible for B
– The ABO locus is found on the long arm of chromosome 9. A patient’s antibody screen is positive
A patient’s antibody screen is positive. A panel shows reactivity with all 11 panel cells at the AHG phase, but the autocontrol is negative. Which is the most likely culprit? a) Anti-Jka b) Anti-K c) Anti-I d) A high-incidence antigen antibody (e.g., anti-k, anti-Kpb, anti-Lub)
O negative blood lacks A, B, and RhD antigens, making it the safest option for emergency transfusions when a recipient's type is unknown.
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