A volley of signals races up through the of the thalamus. And then — you feel it. A massive excitatory postsynaptic potential (EPSP) arrives at your basal dendrites.
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At the NMJ, the enzyme — sitting on the basal lamina — rapidly cleaves ACh into acetate and choline. Choline is taken back up into the LMN via the choline transporter (CHT1) , then reused. A volley of signals races up through the of the thalamus